Yawara Eguchi, Toru Toyoguchi, Kazuhide Inage, Kazuki Fujimoto, Sumihisa Orita, Miyako Suzuki, Hirohito Kanamoto, Koki Abe, Masaki Norimoto, Tomotaka Umimura, Takashi Sato, Masao Koda, Takeo Furuya, Yasuchika Aoki, Junichi Nakamura, Tsutomu Akazawa, Kazuhisa Takahashi, Seiji Ohtori


July 2019, Volume 28, Issue 7, pp 1618 - 1625 Original Article Read Full Article 10.1007/s00586-018-5845-0

First Online: 04 December 2018

Analysis of skeletal muscle mass in women over 40 with degenerative lumbar scoliosis

Purpose

We investigated the involvement of sarcopenia in middle-aged and elderly women with degenerative lumbar scoliosis (DLS).

Methods

A total of 971 women (mean age 70.4 years) were included in our study. These included 87 cases of DLS (mean 73.8 years) and 884 controls (69.8). Lumbar and femur BMD was measured for all participants using dual-energy X-ray absorptiometry. We used a bioelectrical impedance analyzer to analyze body composition, including appendicular skeletal muscle mass index (SMI; appendicular lean mass (kg)/(height (m))2. We determined bone density and skeletal muscle mass in both groups and determined the prevalence of sarcopenia. We examined the correlation between bone density and appendicular muscle mass in both groups. We also examined factors related to scoliosis using logistic regression analysis.

Results

The DLS group showed significantly higher lumbar BMD, lower femur BMD, lower lean mass arm, and lower lean mass leg, and lower lean mass trunk (p 

Conclusions

In middle-aged and elderly women, prevalence of sarcopenia was 59.8% in DLS cases and 42.8% in controls, which revealed a high prevalence in DLS. A decrease in trunk muscle was a significant risk factor for DLS that was independent of age.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.[Figure not available: see fulltext.]


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