Yoshihiro Matsumoto, Kazu Matsumoto, Katsumi Harimaya, Seiji Okada, Toshio Doi, Yukihide Iwamoto


June 2015, Volume 24, Issue 7, pp 1568 - 1573 Original Article Read Full Article 10.1007/s00586-015-3883-4

First Online: 21 March 2015

Purpose

To investigate the prevalence of and to identify independent predictors associated with scoliosis in patients with multiple hereditary exostoses (MHE).

Methods

Fifty patients with MHE were clinically examined, and the diagnosis of scoliosis was made based on radiographs. To classify disease severity, three classes based on the presence of deformities and functional limitations were defined. Significant independent predictors of scoliosis in MHE were statistically analyzed.

Results

Scoliosis was present in 36 patients (MHE-scoliosis) (72 %). In the MHE-scoliosis group, the mean primary curve was 15.3° ± 5.7° (range 10°–34°) and the mean minor curve was 10.6° ± 7° (range 6°–32°). Left curve was predominant (72 %), and the apex was located in the thoracolumbar or lumbar spine in 64 % of patients. Univariable and multivariable analyses confirmed that MHE severity was a significant predictor of moderate scoliosis (≥20°).

Conclusions

Our study confirmed that scoliosis is a common feature of MHE and disease severity is a predictor of moderate scoliosis (≥20°).


Read Full Article